Studies on erythropoiesis. V. The effect of cobalt on the production of erythropoietin.

cythemia in man ansd experimenstal animals. The precise nsechansisnn by which cobalt exerts this actions has not yet beens Clarified comsspletely. Early studies itsdicated that cobalt acts directly by produciisg ass atsoxic coisditioss ins tise marrow,5 while later work suggested an indirect aisoxic effect oss the nsarrow (‘aused by the formatiots of cobalt-ansinso acid coissplexes.#{176} ‘ However, attetsspts